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Multiple additional Smads are present in teleost fishes. Letters in brackets signify additional teleost fish Smads (co-orthologs in relation to human genes). Fly genes are also shown for comparison. Table 5 lists accession numbers for the relevant genes. The tree is produced using TreeBeST and rooted on time. Red boxes signify duplication nodes, while green boxes signify speciation nodes (inferred using the speciation and duplication inference algorithm).
