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. 2009 Mar 5;28(1):31. doi: 10.1186/1756-9966-28-31

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Copyright © 2009 Bai et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Inhibition of angiogenesis within tumor estimated by CD31 immunohistochemical analysis. (A) were representative sections from each group. a: Ad-hEndo+ cisplatin; b: Ad-hEndo; c: cisplatin; d: Ad-null; e: NS. (B) Vessel density was determined via counting the number of the microvessels per high-power field within hot spot area. Values were expressed as means ± SE (5 high power fields/slide). Tumors of the combination group showed smaller number of microvessel count than that of the other groups submitted to cisplatin or Ad-Endo alone, especially the NS (P < 0.05). a: Ad-hEndo+cisplatin; b: Ad-hEndo; c: cisplatin; d: Ad-null; e: NS.