Changes of the subdivided MspI-TRF distribution with aging. Southern blotting smear of MspI-TRF was divided into three portions (>9.4, 9.4 ≥ ≥ 4.4, and 4.4 >). The percentages of densitometry of each portion are shown as columns. (A, Whole population; B, Men; C, Women) The longest telomeric portion decreases with aging and the shortest increases beyond the age of 60. The middle subdivided part (9.4 > > 4.4 kb) did not reveal a clear aging-related change. Horizontal bars depict the standard errors. TRF = terminal restriction fragment.