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Slices were superfused with multiple applications of 10 μM UTP in 5 min. acute (A) or 15–30 min. chronic (B,C) presence of 10 μM cyclopiazonic acid (CPA) or vehicle (0.1% DMSO). (▲ indicates time of UTP superfusion, □ indicates time of drug superfusion). Right panels: Average peak calcium transient amplitudes are shown *, p<0.001.
