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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: Glia. 2009 Apr 15;57(6):634–644. doi: 10.1002/glia.20792

Figure 6. The PLC pathway has a role in purinergic-evoked calcium increases.

Figure 6

(A–C, E) Slices were superfused with multiple applications of 10 μM UTP in the presence of (A) 150 μM neomycin, (B) 100 μM U73122, (C) 100 μM U73343, (E) 100 μM 2-APB. (▲indicates time of UTP superfusion, □ indicates time of drug superfusion). Y axis is normalized peak amplitude. Right panels: Average normalized peak amplitudes and the predicted peak amplitudes for the second application (v) are shown. *, p<0.01. (D) UTP responsive cells (mean ± s.e.m.) from slices incubated 20 min in 0.1% DMSO vehicle (n=4) or 200 μM U73122 (n=10, p=0.0008).

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