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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Cancer Gene Ther. 2008 Nov 14;16(4):362–372. doi: 10.1038/cgt.2008.80

Figure 6.

Figure 6

Determination of anti-adenoviral antibodies following i.c. injection of adenoviral vectors in Syrian hamsters (SHs). (a) Anti-adenoviral antibodies were detected by ELISA in sera from SHs at days 14 and 30 following i.c. injection of AdWT and CRAd-S-pk7 at a 1:10 and 1:100 serum dilutions(P<0.05). (b) A regression analysis showed a significant negative correlation in the number of viral genomic copies found in the noninjected hemisphere and the anti-adenoviral antibody signal (ELISA, OD 450 nm) (P<0.05) and a marginally significant negative correlation of viral genomic copies found in the injected hemisphere and the anti-adenoviral antibody signal (ELISA, OD 450 nm) (P = 0.053).

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