FIG. 3.

Accelerated rejection following presensitization of the host. (A) Representative BLI images of animals following intramuscular allotransplantation of mESCs show an accelerated decrease in BLI signal in animals that were presensitized with both nontransduced mESCs (mESC presens) or irradiated 129/Sv splenocytes (spleno presens) as compared to naïve allogeneic mESC recipients. Color scale bar values are in p/s/cm²/sr. (B) Graphical representation of BLI of mESC survival in the three groups (n = 4–8 per group). Data points represent mean ± SEM; *p < 0.001 mESC vs. spleno presens, **p < 0.001 mESC versus mESC presens (by ANOVA). Dotted line = background BLI signal.