. Author manuscript; available in PMC: 2010 Feb 1.

Published in final edited form as: Calcif Tissue Int. 2008 Dec 12;84(2):126–137. doi: 10.1007/s00223-008-9201-y

Table 1.

Morphometric features of HYP/PHEX mice at 1, 3, and 9 months

	WT		HYP		WT + TG		HYP + G

	Male	Female	Male	Female	Male	Female	Male	Female
N	5	9	8	11	4	4	5	4
Body weight (g)
1 month	23.4 ± 2.5	17.4 ± 1.6	19.0 ± 1.0	17.1 ± 1.4	23.5 ± 1.5	17.8 ± 1.0	21.2 ± 1.2	18.5 ± 2.4
3 months	37.0 ± 4.8	22.4 ± 2.6	25.3 ± 2.4	22.0 ± 2.8	34.8 ± 2.2	23.4 ± 1.8	32.2 ± 2.2	23.3 ± 3.5
9 months	45.0 ± 3.2	27.4 ± 5.9	28.1 ± 5.2	26.8 ± 5.1	43.6 ± 3.3	29.8 ± 5.6	38.2 ± 4.8	30.4 ± 11.3
Length of animal (cm)
1 month	15.7 ± 0.7	13.8 ± 0.8	13.4 ± 0.4	13.5 ± 0.8	15.5 ± 0.4	14.7 ± 0.3	14.4 ± 0.4	14.5 ± 0.6
3 months	17.5 ± 0.9	15.5 ± 1.1	14.5 ± 0.6	14.7 ± 1.1	17.1 ± 0.7	17.2 ± 0.9	16.7 ± 0.9	16.3 ± 0.5
9 months	17.8 ± 0.7	15.3 ± 1.0	14.0 ± 1.0	14.7 ± 1.1	17.9 ± 0.7	17.0 ± 1.2	17.0 ± 0.9	16.1 ± 0.7
BMD (g/cm²)
1 month	0.040 ± 0.002 (5)^a	0.031 ± 0.003 (9)	0.027 ± 0.001 (8)	0.029 ± 0.002 (11)	0.040 ± 0.002 (4)	0.033 ± 0.005 (4)	0.032 ± 0.001 (5)	0.033 ± 0.005 (4)
3 months	ND	0.033 ± 0.002 (2)	0.027 ± 0.001 (2)	0.036 ± 0.008 (5)	0.0299	0.030 ± 0.001 (2)	0.044 ± 0.0004 (2)	0.032 ± 0.007 (3)
9 months	ND	0.046 ± 0.005 (2)	0.043 ± 0.003 (2)	0.050 ± 0.009 (5)	0.0388	0.0401 ± 0.001 (2)	0.056 ± 0.0008 (2)	0.041 ± 0.009 (3)

Note: HYP hypophosphotemic, WT wild type, TG transgene, ND not determined. Values are mean ± SD for N animals. Values in boldface indicate p < 0.01 vs. WT of same sex

n for BMD measurements given in parentheses. For values with no SD, n = 1