. Author manuscript; available in PMC: 2010 Feb 1.

Published in final edited form as: Calcif Tissue Int. 2008 Dec 12;84(2):126–137. doi: 10.1007/s00223-008-9201-y

Table 3.

Histomorphometry of left tibial sections from 9-month-old mice: mean ± SD

	WT	WT + TG	HYP	HYP + TG
Male
N	5	4	8	5
OV/TV (%)	0.31 ± 0.18	0.44 ± 0.13	24.66 ± 13.95^*	5.48 ± 3.36^**
BV/TV (%)	19.6 ± 5.35	19.72 ± 4.37	87.5 ± 19.7^*	24.7 ± 18.8^**
OsTh (µm)	1.72 ± 0.24	2.1 ± 0.39	16.02 ± 6.05^*	7.74 ± 1.06^**
TbN (per mm²)	4.1 ± 0.75	4.38 ± 0.67	5.64 ± 0.48	3.87 ± 2.04
OV/BV (%)	1.56 ± 0.80	2.20 ± 0.23	46.44 ± 22.02^*	25.49 ± 5.94
Female
N	4	5	17	3
OV/TV (%)	0.38 ± 0.11	0.29 ± 0.12	11.55 ± 9.4^*	2.86 ± 1.33^**
BV/TV (%)	12.5 ± 5.02	8.42 ± 2.51	37.1 ± 18.1^*	16.9 ± 7.7
OsTh (lm)	2.03 ± 0.32	2.11 ± 0.64	10.02 ± 4.64^*	6.01 ± 1.2
TbN (per mm²)	2.68 ± 0.73	2.14 ± 0.75	4.5 ± 1.52	3.1 ± 0.5
OV/BV (%)	3.17 ± 0.83	3.74 ± 1.88	27.1 ± 12.7^*	19.5 ± 10.3

Note: WT wild type, TG transgene, HYP hypophosphatemia, OV/TV osteoid area/tissue area, BV/TV bone volume/tissue volume, OsTh osteoid thickness, TbN trabecular number, OV/BV percentage osteoid.

p < 0.01 vs. WT;

^**

p < 0.01 vs. same genotype without the TG