Fig. 1.

Structure of the PsV-F capsid. (A) Radially color-coded surface view of 8.0-Å cryoEM structure, in stereo. (B) Radially color-coded surface view of X-ray crystal structure calculated at 8.0-Å resolution. (C) The Cα trace of the PsV-F capsid structure viewed along an icosahedral 2f axis. The CPA and CPB molecules are colored red and yellow, respectively. Icosahedral 2f, 3f, and 5f symmetry axes are marked. (D) A CP dodecamer with the 4 possible CPA–CPB dimers (A₁–B₁, A₁–B₂, A₁–B₃, and A₁–B₅). The biologically relevant one, A₁–B₁, is shown in red and yellow, whereas its 2f-related counterpart, A₂–B₂, in shown in magenta and light orange. (E) Molecular contacts made by CPA–CPB dimers at the icosahedral 2f (green), 3f (cyan), and 5f (purple) axes. The colored volume shows only structure elements buried at the intermolecular interfaces; thus, the size of the surface shown is directly proportional to the size of buried surface.