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ASPP2+/− thymocytes have an attenuated apoptotic response to γ-irradiation. Flow cytometry on ASPP2+/+ or ASPP2+/− primary thymocytes 4 h after 5-Gy γ-irradiation (right column) or 0-Gy γ-irradiation (left column). The percentage of cells in each quadrant (relative to total cells) is indicated. The fold-increase in apoptosis between 0-Gy and 5-Gy γ-irradiated thymocytes was determined by the increase in percentage of Annexin V-stained cells (lower right plus upper right quadrants).
