Table 2.
List of affected microRNA species by acetaminophen overdose
| Liver tissues (24 h after exposure) |
Plasma samples (24 h after exposure) |
||
|---|---|---|---|
| miRNA name | Fold change (log2) treated/control array hyb intensity | miRNA name | Fold change (log2) treated/control array hyb intensity |
| mmu-miR-29b | −3.06 | mmu-miR-710 | −4.69 |
| mmu-miR-122 | −2.71 | mmu-miR-720 | −4.32 |
| mmu-miR-15a | −2.65 | mmu-miR-205 | −3.77 |
| mmu-miR-29a | −2.65 | mmu-miR-711 | −3.70 |
| mmu-miR-130a | −2.28 | mmu-miR-486 | −3.63 |
| mmu-miR-29c | −2.14 | mmu-miR-133a | −2.92 |
| mmu-miR-192 | −2.12 | mmu-miR-124 | −2.87 |
| mmu-miR-194 | −2.11 | mmu-miR-133b | −2.76 |
| mmu-miR-212 | −2.06 | mmu-miR-135a* | −2.42 |
| mmu-let-7c | −2.04 | mmu-miR-202-3p | −2.13 |
| mmu-let-7b | −1.86 | mmu-miR-125a-3p | −2.12 |
| mmu-miR-487b | −1.82 | mmu-miR-125b-5p | −2.07 |
| mmu-miR-26a | −1.75 | mmu-miR-483 | −2.00 |
| mmu-miR-21 | −1.59 | mmu-miR-1224 | −1.91 |
| mmu-miR-101b | −1.48 | mmu-miR-23a | −1.67 |
| mmu-miR-19b | −1.38 | mmu-miR-712 | −1.57 |
| mmu-miR-193 | −1.28 | mmu-miR-451 | −1.41 |
| mmu-miR-30a | −1.17 | mmu-miR-26a | −1.20 |
| mmu-miR-297a | 2.58 | mmu-miR-721 | −1.15 |
| mmu-miR-483 | 2.89 | mmu-miR-680 | 1.02 |
| mmu-let-7d* | 3.09 | mmu-miR-365 | 1.14 |
| mghv-miR-M1-2 | 3.12 | mmu-miR-30c | 1.16 |
| mmu-miR-709 | 3.19 | mmu-let-7d* | 1.45 |
| mmu-miR-574-3p | 3.23 | mmu-miR-30e | 1.49 |
| mmu-miR-466 g | 3.27 | mmu-miR-574-5p | 1.49 |
| mmu-miR-466 h | 3.27 | mmu-miR-30a | 1.62 |
| mmu-miR-466f-3p | 3.34 | mmu-miR-15a | 1.73 |
| mmu-miR-1224 | 3.36 | mmu-miR-107 | 1.79 |
| mmu-miR-574-5p | 3.40 | mmu-miR-19b | 1.88 |
| mmu-miR-467a* | 3.42 | mmu-miR-294* | 2.10 |
| mmu-miR-689 | 3.44 | mmu-miR-27b | 2.23 |
| mmu-miR-467b* | 3.56 | mmu-miR-29a | 2.45 |
| mmu-miR-207 | 3.56 | mmu-let-7 g | 2.48 |
| mmu-miR-669c | 3.58 | mmu-miR-29b | 2.64 |
| mmu-miR-483* | 3.61 | mmu-miR-148a | 2.78 |
| mmu-miR-877* | 3.65 | mmu-miR-22 | 2.92 |
| mmu-miR-467e* | 3.68 | mmu-miR-21 | 3.40 |
| mmu-miR-468 | 3.74 | mmu-miR-130a | 3.41 |
| mmu-miR-466c-5p | 3.75 | mmu-miR-101b | 3.48 |
| mmu-miR-297b-3p | 3.84 | mmu-miR-29c | 3.71 |
| mmu-miR-672 | 4.02 | mmu-miR-193 | 4.02 |
| mmu-miR-671–5p | 4.07 | mmu-miR-685 | 4.82 |
| mmu-miR-197 | 4.27 | mmu-miR-192 | 6.32 |
| mmu-miR-485* | 4.33 | mmu-miR-122 | 8.89 |
| mmu-miR-188–5p | 4.34 | ||
| mmu-miR-328 | 4.37 | ||
| mmu-miR-669a | 4.52 | ||
| mmu-miR-721 | 4.63 | ||
| mmu-miR-466d-3p | 4.70 | ||
| mmu-miR-710 | 5.85 | ||
| mmu-miR-711 | 6.95 | ||
The common miRNA species that affected by acetaminophen overdose between tissue and plasma are listed in bold characters. hyb, hybridization.