Figure 2.

(a) Infectious and non-infectious viral levels simulated by the basic model (1). (b) The difference between non-infectious and infectious HIV-1 RNA concentrations. Shortly after initiation of potent antiretroviral therapy, the difference between non-infectious and infectious viral levels (base 10 logarithm) approaches a constant (~ 0.27). The parameter values used in the simulation are: λ = 104 ml−1 day−1, dT = 0.01 day−1, k = 2.4 × 10−8 ml day−1, αL = 0.001, ∈RT = 0, ∈PI = 0.65, dL = 0.004 day−1, a = 0.1 day−1, δ = 1 day−1, N = 4000, c = 23 day−1.