Figure 3.

Schematic representation of asymmetric division of latently infected cells upon antigenic stimulation. Suppose a daughter cell has probability p_L to stay in the latent state, and probability (1 − p_L) to differentiate into a productively infected cell. (a) The probability that both two daughter cells are in the latent state is $p_L^2$; (b) The probability that one daughter cell is latently infected and the other is activated infected is 2p_L(1 − p_L); (c) The probability that two daughter cells are both activated infected is (1 − p_L)². The expectation of the number of latently infected cells generated every time a parental cell divides is $2·p_L^2+1·2p_L(1-p_L)=2p_L$.