Table 1. Nucleotide and amino acid sequence comparisons of HPeV7 candidate prototype PAK5045 with the HPeV prototypes*.
| Sequence | % Nucleotide (amino acid) identity |
|||||
|---|---|---|---|---|---|---|
| HPeV1 | HPeV2 | HPeV3 | HPeV4 | HPeV5 | HPeV6 | |
| 5′ UTR | 87.6 | 86.8 | 95.9 | 90.2 | 86.7 | 89.8 |
| VP0 | 71.0 (76.8) | 69.6 (75.8) | 68.3 (72.3) | 69.7 (75.1) | 70.1 (75.4) | 69.7 (73.7) |
| VP3 | 69.5 (75.3) | 69.9 (74.1) | 73.2 (83.9) | 70.3 (77.5) | 69.7 (74.0) | 68.8 (74.0) |
| VP1 | 65.8 (69.9) | 66.6 (69.5) | 68.9 (77.0) | 67.8 (68.6) | 64.7 (66.4) | 63.9 (65.0) |
| 2A | 77.9 (89.3) | 75.2 (84.6) | 77.5 (85.9) | 80.8 (89.3) | 80.5 (89.9) | 76.5 (85.9) |
| 2B | 80.1 (95.9) | 76.8 (95.1) | 86.1 (99.2) | 83.6 (99.2) | 83.6 (97.5) | 78.7 (96.7) |
| 2C | 78.9 (91.5) | 76.5 (86.6) | 83.8 (96.0) | 85.9 (97.0) | 80.9 (94.5) | 79.5 (90.0) |
| 3A | 76.6 (88.0) | 76.1 (83.8) | 81.8 (94.0) | 87.5 (96.6) | 78.9 (82.9) | 76.1 (89.7) |
| 3B | 73.3 (90.0) | 75.0 (90.0) | 76.7 (85.0) | 85.0 (95.0) | 76.7 (90.0) | 70.0 (90.0) |
| 3C | 81.3 (98.0) | 81.2 (98.0) | 83.5 (98.0) | 86.3 (98.0) | 80.3 (99.0) | 83.0 (99.0) |
| 3D | 83.2 (94.9) | 82.8 (94.0) | 88.7 (96.8) | 90.8 (97.2) | 83.8 (95.9) | 83.6 (95.3) |
| 3′ UTR | 85.1 | 89.8 | 95.5 | 94.4 | 85.2 | 83.0 |
| ORF | 76.3 (86.7) | 75.6 (84.8) | 79.5 (89.1) | 80.8 (88.5) | 77.0 (86.6) | 76.0 (85.4) |