Table 2. VP1 amino acid sequence comparisons of HPeV types*.
| Type | Average (range) of VP1 amino acid identities, % |
||||||
|---|---|---|---|---|---|---|---|
| HPeV1 | HPeV2 | HPeV3 | HPeV4 | HPeV5 | HPeV6 | PAK5045 | |
| HPeV1 | 94.7 (81.8–100.0) | 78.3 (71.7–80.0) | 71.2 (61.9–73.9) | 75.6 (69.7–78.4) | 72.6 (66.7–74.9) | 78.2 (71.9–81.8) | 68.1 (64.6–69.9) |
| HPeV2 | 99.4 (99.1–100.0) | 71.4 (65.5–72.6) | 74.9 (74.3–76.1) | 71.8 (70.4–72.6) | 73.7 (73.5–73.9) | 69.5 (–) | |
| HPeV3 | 97.3 (85.8–100.0) | 70.8 (66.4–71.7) | 66.8 (60.6–68.6) | 73.9 (66.8–75.7) | 77.6 (69.9–78.8) | ||
| HPeV4 | 97.0 (96.6–97.8) | 78.3 (75.9–80.2) | 72.8 (72.3–73.2) | 68.4 (68.1–68.6) | |||
| HPeV5 | 96.9 (94.8–100.0) | 72.0 (71.0–72.7) | 66.1 (65.5–66.4) | ||||
| HPeV6 | 97.2 (95.7–98.7) | 64.9 (64.6–65.0) | |||||
| PAK5045 | – | ||||||
*92 full-length VP1 amino acid sequences were obtained from GenBank, including 46 HPeV1, 4 HPeV2, 31 HPeV3, 3 HPeV4, 4 HPeV5 and 4 HPeV 6 VP1 amino acid sequences. The accession nos. are AAA72291, AAB32466, AAB23363, AAC79756, ABC41566, ABK54353, ABS82455, ABS82457–82462, ABX79460, ABX79453, BAC23086, BAD05057–05062, BAF63403, BAF76536–6596, CAA06679, CAI64373, CAJ84483~84484, NP_046804, NP_740386, Q66578, and Q9YID8. HPeV, human parechoviruses; VP1, viral protein 1.