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letter
. 2009 Feb;15(2):355–357. doi: 10.3201/eid1502.081066

Table. Clinical course of illness in 10-month-old boy with systemic infection with enteric adenovirus and Haemophilus influenzae disease, Thailand, 2003–2004*.

Date, 2003 Events
Dec 7 Patient hospitalized with 6-day history of fever >38°C and somnolence; blood culture positive for Hemophilus influenzae; isolate not typed (unavailable for further characterization)
Dec 9 CSF results: pleocytosis (2,710 leukocytes/mm3, 94% neutrophils); protein 178 mg/dL; glucose 11 mg/dL; CSF culture positive for H. influenzae; CSF Gram stain positive for gram-negative coccobacilli; antimicrobial drug treatment (ceftriaxone) started
Dec 11 New onset seizures, ataxia, and maculopapular rash on entire trunk and all extremities; no diarrhea or respiratory symptoms; brain ultrasound scan results within normal limits; anticonvulsant therapy (phenobarbital) started
Dec 12 CSF results: pleocytosis (100 leukocytes/mm3, 60% neutrophils, 40% monocytes); protein 131.6 mg/dL; glucose 31 mg/dL; CSF bacterial culture, results negative; CSF Gram stain results negative; patient enrolled in the encephalitis study; initial specimens for the study collected
Dec 22 Brain ultrasound scan results within normal limits; antimicrobial drug treatment (ceftriaxone) discontinued
Dec 23 CSF bacterial culture results negative; CSF Gram stain results negative; anticonvulsant therapy (phenobarbital) discontinued
Dec 27 Patient discharged in improved condition; discharge diagnosis: H. influenzae meningitis and septicemia
Jan 7† Follow-up visit: full recovery without sequelae; convalescent-phase serum specimen obtained

*CSF, cerebrospinal fluid.
†2004.