TABLE 3.
Studies comparing overall taste, tolerability and symptoms of Pico-Salax (PCSLX)* compared with oral sodium phosphate (NaP) or polethylene glycol solution (PEG)
| Reference, year | Cleansing agent
|
Procedure | Taste | Tolerability | Symptoms
|
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| PCSLX patients, n | NaP patients, n | PEG patients, n | Nausea/vomiting | Discomfort | Dizziness | Thirst | ||||
| Hamilton et al (13), 1996 | 25 | – | 27 | Colonoscopy/ACBE | Not tested | Not tested | PEG>PCSLX | – | – | – |
| Schmidt et al (23), 2004† | 182 | 190 | – | Colonoscopy | PCSLX>NaP | PCSLX>NaP | NaP>PCSLX | NaP>PCSLX | NaP>PCSLX | NaP>PCSLX |
| Yoshioka et al (24), 2000 | 77 | 76 | – | Colonoscopy | Not tested | Not tested | No difference‡ | No difference‡ | Not tested | Not tested |
| Macleod et al (25), 1998 | 83 | 111 | – | ACBE | PCSLX>NaP | PCSLX>NaP | NaP>PCSLX | No difference‡ | Not tested | Not tested |
| Hawkins et al (27), 1996 | 45 | – | 47 | ACBE | Not tested | Not tested | PEG>PCSLX | PEG>PCSLX | Not tested | Not tested |
*
Registered trademark of Ferring Pharmaceuticals Inc, Canada;
†
Data not presented, PCSLX three doses;
‡
No difference between NaP and PCSLX because n values might be too small. ACBE Air contrast barium enema