Table 2.
Predictors of death among subjects with HF in the community
Models not including ejection fraction | Models including ejection fraction | |||
---|---|---|---|---|
Predictor Variable | HR (95% CI) | p-value | HR (95% CI) | p-value |
All Cause Death | ||||
Age (per year increase) | 1.057 (1.049, 1.064) | <0.001 | 1.058 (1.050, 1.065) | <0.001 |
Male sex | 1.28 (1.10, 1.49) | 0.001 | 1.27 (1.09, 1.48) | 0.002 |
Diabetes mellitus | 1.44 (1.21, 1.72) | <0.001 | 1.44 (1.21, 1.71) | <0.001 |
Smoking | 1.38 (1.18, 1.61) | <0.001 | 1.39 (1.19, 1.62) | <0.001 |
Documented coronary disease | 0.93 (0.80, 1.08) | 0.32 | 0.93 (0.80, 1.07) | 0.29 |
Severe chronic kidney disease | 2.23 (1.75, 2.83) | <0.001 | 1.96 (1.51, 2.54) | <0.001 |
Ejection fraction ≥ 50% | 0.88 (0.74, 1.04) | 0.15 | ||
| ||||
Cardiovascular Death | ||||
Age (per year increase) | 1.055 (1.044, 1.065) | <0.001 | 1.055 (1.044, 1.065) | <0.001 |
Male sex | 1.26 (1.03, 1.54) | 0.026 | 1.22 (1.00, 1.48) | 0.054 |
Diabetes mellitus | 1.47 (1.17, 1.85) | <0.001 | 1.46 (1.16, 1.82) | <0.001 |
Smoking | 1.27 (1.04, 1.55) | 0.020 | 1.24 (1.01, 1.52) | 0.039 |
Documented coronary disease | 1.15 (0.95, 1.40) | 0.16 | 1.12 (0.93, 1.35) | 0.23 |
Severe chronic kidney disease | 2.38 (1.76, 3.23) | <0.001 | 2.10 (1.52, 2.88) | <0.001 |
Ejection fraction ≥ 50% | 0.71 (0.57, 0.89) | 0.006 |
Coronary disease defined as prior myocardial infarction, coronary artery bypass grafting or angiographically defined significant coronary artery disease.