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. Author manuscript; available in PMC: 2010 Jan 3.
Published in final edited form as: Tetrahedron. 2009 Jan 3;65(1):70–76. doi: 10.1016/j.tet.2008.10.019

Table 4.

Hydrolytic kinetic resolutions using Co(II) salen complex.21

graphic file with name nihms83407f13.jpg
entry oxirane recovery (%)a ee (%)b [α]D
1 graphic file with name nihms83407t18.jpg 46 >99 −24.0 (−23.7 (lit))
2 graphic file with name nihms83407t19.jpg 45 >99 −17.2 (+19.3 (lit (ent)))
3 graphic file with name nihms83407t20.jpg 42 >99 −9.8
4c graphic file with name nihms83407t21.jpg 43 >89d +13.8 (+15.5 (lit))
a

Isolated chromatographically pure material. Monitored by 1H NMR.

b

HPLC (Regis (R,R)-Whelko-O1 column

c

(S,S) Co(II) salen complex

d

Based upon specific rotaton; unable to resolve enantiomers by HPLC