Table 3.
Disease Model | q† | α | β | γ | Deviance | p-Value |
---|---|---|---|---|---|---|
General Under H0 | 0.39 | 6.6 × 10−6 | 2.06** | 1.05 | 1.17* | 0.2795 |
Dominant Under H0 | 0.34 | 5.5 × 10−6 | 2.45** | 2.45** | 4.74 | 0.0937 |
Dominant Under Ha |
0.38 |
7.3 × 10−6 |
1.57 |
1.57 |
0.21 |
0.6456 |
Likelihood Ratio Test of H0 vs. Ha | 4.52 | 0.0334 |
This is the general χ2 statistic instead of the deviance defined as (8).
Significantly different from 1 at 0.05 level.
q is the frequency of the minor allele C.