Table 5.

Fitting recessive disease models (β is fixed at 1) to ten case-control studies analyzed by Wittke-Thompson, Pluzhnikov and Cox (2005) under the alternative hypothesis H_a: the genotype is not in HWE in the study population. Table 4 has more study details.

Study	Genotype Distributions
PubMed ID	Patients	Controls	Kp	q	p0	p1	α	γ	Deviance (df=1)	p-value
11468325	137−34−8	180−40−8	.06	0.127	.781	.182	0.0594	1.265	0.181	.671
11124296	42−24−32	95−38−33	.01	.324	.551	.249	0.00842	1.939	1.233	.267
11889073	28−64−94	114−560−553	.05	.671	.102	.452	0.0445	1.275	8.760	.003
12631667	2−20−129	5−22−122	.05	.897	.025	.153	0.0406	1.282	0.912	.339
9607207	6−10−21	8−48−19	.05	.563	.142	.589	0.0296	3.566	3.832	.050
10712418	227−361−218	197−349−186	.1	.489	.278	.466	0.0980	1.079	0.771	.380
10680782	276−97−14	221−64−15	.05	.166	.718	.232	0.0507	0.724	1.107	.292
10430441	109−125−31	154−203−36	.15	.346	.403	.502	0.1464	1.256	0.678	.410
11027931	2−6−82	0−22−163	.01	.934	.010	.111	0.00735	1.411	3.504	.061
12426569	416−504−213	378−512−116	.01	.364	.388	.496	0.00919	1.764	1.385	.239