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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Genet Epidemiol. 2009 Apr;33(3):275–280. doi: 10.1002/gepi.20381

Table 6.

Likelihood ratio test of population HWE for ten case-control studies analyzed by Wittke-Thompson, Pluzhnikov and Cox (2005).

Study
Genotype Distributions
PubMed ID/Disease/Gene Patients Controls Difference of Deviance(df=1) p-value
11468325/Alzheimer disease/CST3 137−34−8 180−40−8 7.696 .006
11124296/Macular degeneration/mEPHX 42−24−32 95−38−33 38.093 <.001
11889073/Colorectal cancer/MTHFR 28−64−94 114−560−553 0.810 .368
12631667/Crohn disease/CYP1A1 2−20−129 5−22−122 5.474 .019
9607207/Hypertension(nephroangiosclerosis)/ACE 6−10−21 8−48−19 3.697 .055
10712418/Myocardial infarction/TF-1208 227−361−218 197−349−186 5.638 .018
10680782/Multiple sclerosis/GSTM3 276−97−14 221−64−15 8.937 .003
10430441/Stroke/NOS3 109−125−31 154−203−36 6.997 .008
11027931/Venous thrombosis/β-fibrogen 2−6−82 0−22−163 1.612 .204
12426569 /MI/lymphotoxin-α gene 416−504−213 378−512−116 7.181 .007