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. Author manuscript; available in PMC: 2009 Mar 19.
Published in final edited form as: Am J Physiol Cell Physiol. 2008 Mar 5;294(5):C1288–C1297. doi: 10.1152/ajpcell.00033.2008

Fig. 4.

Fig. 4

Diffusion of mammalian CaM (mCaM488) within the diaphragm. A: time course for “wash-in” of mCaM488 (1 μM) immediately after fiber permeabilization. Data were best fit by a double exponential with time constants of 1.9 ± 1.1 and 12.0 ± 2.6 min (n = 6 fibers). B: time course for “wash-out” of mCaM488 (1 μM). The binding of CaM488 was allowed to reach equilibrium (45 min) before the start of the “wash-out.” The data were best fit by a single exponential, with a time constant of 7.8 ± 0.1 min and an offset of 0.55 ± 0.002 (n = 4 fibers).