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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Gynecol Oncol. 2008 Nov 12;112(1):47–54. doi: 10.1016/j.ygyno.2008.09.043

Table 3.

Serum Biomarker Levels Across Ovarian Epithelial Carcinoma Subtypes

Biomarker Levels (mean pg/ml ± 95% CI) Mann-Whitney Significance

Benign CEM Carcinoma Serous Carcinoma Benign vs. CEM Benign vs. Serous CEM vs. Serous
CA 1251 14.15±4.61 49.65±15.04 123.9±51.17 *** ** ***
CA 72-41 2.04±.285 13.5±7.9 4.39±2.06 *** **
CD40L 19457±4732 23522±4994 16414±5929 *
Cyfra 21-1 891±222 2323±718 2633±886 *** ***
EGFR 8548±344 7233±397 7552±636 *** **
FSH2 37487±5344 24744±5182 36471±7751 **
HE4 5476±4357 74816±42866 43857±18512 *** ***
IGFBP-1 10178±1891 15509±3660 9734±3536 *
IL-10 15.67±2.63 32.48±10.78 20.79±4.31 *** **
IL-2R 355.7±57.2 541.6±105.2 651.6±169.8 *** ***
IL-6 19.67±3.4 31.55±5.87 27.07±9.01 ***
IL-7 8.5±.864 11.6±1.85 10.2±1.69 *** *
IL-8 15±3.91 24.8±15.17 16.9±5.24 ** *
IP-10 49.86±5.35 42.4±5.71 72.53±15.54 * *** ***
LH2 19118±2435 15767±2982 22441±4496 ** **
MMP-2 150963±8262 131903±9126 137652±14133 **
MMP-9 212302±34252 361810±62411 250084±64652 *** **
MPO 91818±21710 123134±30713 80550±30403 * **
SMRP3 44227±19250 43804±15896 117660±49778 *** ***
sVCAM-1 876645±68143 772258±66047 796917±70051 **
TgII4 9.44±1.38 14.34±1.61 14.95±3.09 *** ***
TNF-R2 1515±137 1798±186 1836±228 * **
tPAI-1 35876±3432 47987±4514 36723±4949 *** **
1

U/ml,

2

IU/ml,

3

pM,

4

mU/ml CEM: clear cell, endometrioid, mucinous carcinoma

*

-p<0.05,

**

-p<0.01,

***

-p<0.001