. Author manuscript; available in PMC: 2009 Mar 19.

Published in final edited form as: Genes Immun. 2008 Jun 5;9(5):462–469. doi: 10.1038/gene.2008.38

Table 1.

ICAM-1 genotype frequencies and single marker family-based association analysis with severe malaria.

SNP	Major Allele	Minor Allele	Parents	Cases	S	E(S)	Var(S)	P-value
SNP	Major Allele	Minor Allele	MAF	MAF	S	E(S)	Var(S)	P-value
rs5490	A	C	26.0	26.0	429	430.0	190.50	0.94
rs5030340	C	T	5.5	5.5	100	105.0	52.00	0.49
rs5030344	G	A	4.2	4.3	87	86.5	43.25	0.94
rs5030351	C	T	24.6	24.8	414	417.5	183.75	0.80
rs5491	A	T	23.9	23.7	687	688.5	303.75	0.93
rs281432	G	C	24.8	24.7	383	398.5	180.25	0.25
rs5496	G	A	9.5	9.7	176	179.5	88.25	0.71
rs5498	A	G	11.4	11.0	346	368.0	182.00	0.10
rs3093030	C	T	5.8	5.6	100	112.0	55.50	0.11
rs281438	T	G	46.0	46.6	684	683.5	237.25	0.97
rs2569693	C	T	5.5	5.2	87	89.5	43.75	0.71
rs281439	C	G	38.8	38.6	583	589.5	236.25	0.67
rs281440	A	G	31.9	31.0	461	478.5	202.75	0.22
rs2075741	G	C	12.2	11.8	221	236.5	111.75	0.14
rs11575074	G	A	9.7	9.6	172	182.0	89.00	0.29

Minor allele frequencies (MAF, %) for parents and affected offspring. FBAT statistic ‘S’, expected FBAT statistic ‘E(S)’, variance ‘Var(S)’ and P-value are reported under the additive model for transmissions of the minor allele.