Fig. 2.
NCSs are specific to human endometrium. Indirect mAb414 fluorescence on paraffin sections of various human (A-J) and baboon tissues (K,L). (A-J) Samples from commercial tissue arrays. One example out of six specimens each of human breast (A), lung (B), kidney (C), liver (D), esophagus (E), stomach (F), colon (G), and rectum (H) tissue. One example out of 59 specimens each of human control endometrium (I) and endometria with adenocarcinomas (J). (K,L) Two examples out of 19 baboon secretory endometrial biopsies. Note only control human secretory endometrium contains NCSs (arrows). Nuclear pore complex staining is generally better in endometria but, despite high background labeling, can be distinguished in the other tissues and should therefore reveal NCSs if present. Scale bar: 10 μm.