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. 2008 Jun;27(12):3182–3190. doi: 10.1111/j.1460-9568.2008.06260.x

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© The Authors (2008). Journal Compilation © Federation of European Neuroscience Societies and Blackwell Publishing Ltd

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Fig. 5 — Dexmedetomidine dose not affect the frequency or amplitude of spontaneous EPSCs in SG neurons. (A) Continuous chart recording of sEPSCs before and during the application of dexmedetomidine (3 μm) (upper trace). Four consecutive traces of sEPSCs for a period indicated by a short bar below the chart recording are shown on an expanded time scale (lower traces). Holding potential = −70 mV. (B) Cumulative distributions of the amplitude (left) and the inter-event interval (right) of sEPSCs before (dashed line) and during the application of dexmedetomidine (continuous line). Dexmedetomidine had no significant effect on the amplitude (P> 0.05; Kolmogorov–Smirnov test) or the inter-event interval distribution (P> 0.05).