Table 1.
Baseline characteristics
| Characteristics | Usual care (n = 538) | Intervention (n = 565) | Total (n = 1103) |
|---|---|---|---|
| Female, n (%) | 83 (15.4) | 71 (12.6) | 154 (14.0) |
| Age (years), mean (SD) | 56.9 (4.9) | 56.8 (5.1) | 56.8 (5.1) |
| White*, n (%) | 534 (99.3) | 525 (92.9) | 1059 (96.0) |
| Weight (kg), mean (SD) | 87.8 (15.6) | 87.8 (15.0) | 87.8 (15.3) |
| Height (cm), mean (SD) | 173.2 (8.6) | 173.3 (8.5) | 173.2 (8.5) |
| BMI (kg/m2), mean (SD) | 29.2 (4.6) | 29.2 (4.5) | 29.2 (4.5) |
| SBP† (mmHg), mean (SD) | 158.6 (14.0) | 157.0 (14.0) | 157.8 (14.0) |
| DBP† (mmHg), mean (SD) | 94.0 (9.7) | 93.3 (8.4) | 93.6 (9.1) |
| Total cholesterol† (mmol/l), mean (SD) | 5.9 (1.0) | 5.9 (1.0) | 5.9 (1.0) |
| LDL-C† (mmol/l), mean (SD) | 3.9 (1.0) | 3.9 (0.9) | 3.9 (0.9) |
| HDL-C† (mmol/l), mean (SD) | 1.4 (0.4) | 1.4 (0.4) | 1.4 (0.4) |
| Triglycerides† (mmol/l), mean (SD) | 2.1 (1.3) | 2.1 (1.2) | 2.1 (1.3) |
| History of dyslipidaemia, n (%) | 93 (17.3) | 101 (17.9) | 194 (17.6) |
| Dyslipidaemia according to lipids/medication use, n (%) | 267 (49.6) | 300 (53.1) | 567 (51.4) |
| Smoker†, n (%) | 257 (55.7) | 273 (52.1) | 530 (53.8) |
| History of non-CHD cardiac disorders‡, n (%) | 19 (3.5) | 15 (2.7) | 34 (3.1) |
| 10-year predicted risk of CHD*, mean (SE) | 16.9 (0.26) | 17.2 (0.25) | 17.1 (0.17) |
*
p < 0.01.
†
Data are for the efficacy analysis population only (n = 461 usual care; 524 intervention).
‡
The most common cardiac disorder in both groups was arrhythmia (1.6% intervention and 3.0% usual care). To convert mmol/l to mg/dl divide by 0.02586 for total cholesterol, LDL-C and HDL-C values, and by 0.01129 for triglycerides. SD, standard deviation; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; CHD, coronary heart disease.