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. 2008 Oct;62(10):1484–1498. doi: 10.1111/j.1742-1241.2008.01872.x

Table 2.

Change in absolute and modifiable Framingham 10-year risk of CHD

Usual care (N = 461) Intervention (N = 524)
Absolute Framingham risk
    Baseline, mean (SE) 16.9 (0.26) 17.2 (0.25)
    Month 6, mean (SE) 13.7 (0.27) 12.5 (0.25)
    Adjusted change in risk from baseline to month 6, LS mean (95% CI)** −4.9§ (−5.5 to −4.3) −6.3§ (−6.9 to −5.7)
Modifiable Framingham risk (% above ‘normal’)
    Baseline, mean (SE) 221 (15.7) 192 (12.4)
    Month 6, mean (SE) 117 (9.3) 87 (7.8)
    Adjusted change in risk from baseline to month 6, LS mean (95% CI)* −96§ (−115 to −78) −115§ (−133 to −97)
*

p < 0.05.

**

p < 0.001, for intervention vs. usual care.

§

p < 0.001 vs. baseline.

Data were adjusted for baseline risk and other covariates.

Defined as the risk for a non-smoker of the same age, gender, not receiving antihypertensive treatment and with total cholesterol = 4.9 mmol/l (189 mg/dl), high-density lipoprotein cholesterol = 1.0 mmol/l (40 mg/dl) for males or 1.2 mmol/l (46 mg/dl) for females = 1.3 mmol/l (50 mg/dl), and systolic blood pressure = 139 mmHg (38). SE, standard error; LS, least square; CI, confidence interval.