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Reaction products of PAI wt and selected mutants with LA analogs and lipids
| Protein | Substrate | Product |
|---|---|---|
| PAI wt | Methyl ester LA | 10,12-CLA (traces) |
| R88S, F193A, R88S/F193A | 10,12-CLA (3-5%) | |
| PAI wt | Linoleyl-CoA | 10,12-CLA-CoA |
| R88S, F193A, R88S/F193A | 10,12-CLA-CoA | |
| PAI wt | Tri-linoleyl-glycerol | None |
| R88S, F193A, R88S/F193A | None | |
| PAI wt | Di-linoleyl-phosphatidylcholine | None |
| R88S, F193A, R88S/F193A | None |
