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. 2001 Feb 3;322(7281):276–278. doi: 10.1136/bmj.322.7281.276

Table.

Results of investigations of patients with abnormal results for liver function

No of patients Result
Review of doctors' notes for patients not under hospital follow up (n=342)
 38 Repeated liver function tests normal when requested by doctor
39 Died
30 Left practice (no follow up possible)
69 No further investigation appropriate (age, cancer, congestive heart failure)
9 Referred to hospital, awaiting outpatient appointment
157 Partial or no investigation
Positive test results in patients being managed by doctor (n=7)
 3 Antimitochondrial antibody
2 Increased ferritin concentration
1 Bile duct 9 mm on ultrasonography, stones in gall bladder
1 Smooth muscle antibody
Final diagnoses fully investigated (n=157)
 36 Normal result for repeated liver function test requested by liver clinic
18 Normal results for serological tests; declined liver biopsy
6 Normal liver on biopsy
42 Alcoholic liver disease (23 with cirrhosis)
26 Fatty liver or non-alcoholic steatohepatitis (11 fibrotic on biopsy)
5 Primary biliary cirrhosis
4 Primary haemochromatosis
2 Hepatitis B
6 Hepatitis C
2 Autoimmune hepatitis
2 Common bile duct stones
1 Primary sclerosing cholangitis
1 α1 antitrypsin deficiency
6 Cryptogenic hepatitis