Figure 5.

Change in total lactate levels in medium in normoxic (N) and hypoxic (H) neurons during incubation with [1-¹³C]glucose indicating increase in glycolysis. Nn₄₅ & Nn₁₂₀: Normoxic cells incubated under normoxia for 45 & 120 min, respectively, Hn₄₅ & Nn₁₂₀: Hypoxic cells incubated under normoxia for 45 & 120 min, respectively, Hh₁₂₀: Hypoxic cells incubated under hypoxia for 120 minutes. Each bar is represented by mean ± SD from at least three different experiments. * - p<0.0001 when comparing normoxic and hypoxic neurons at respective time points. $ - p<0.0001 when comparing normoxic and hypoxic neurons under normoxic incubation with hypoxic neurons under hypoxic incubation for 120 minutes.