Table 4 Treatment regimens and co‐interventions used in studies of nebulised magnesium sulphate.

Study	Magnesium regimens		Total amount magnesium used	Control regimen	Bronchodilator regimen	Co‐interventions
Aggarwal	1 ml MgSO4 (500 mg) (3 doses, 20 min apart) with β‐agonist		1500 mg (3×500 mg)	1.5 ml distilled water7.5 ml normal saline	Salbutamol 1 ml	IV hydrocortisone + salbutamolDiscretion physician
Drobina	125 mg MgSO4 0.25 ml of 50% solution (3 doses, 20 min apart) with β‐agonist		375 mg (3×125 mg)	0.25 ml saline solution	5 mg/ml albuterol + 2.5 ml ipratropium bromide	50 mg oral prednisolone
Kokturk	Iso‐osmolar MgSO4 (6.3%, 145 mg/dose) (20 min intervals) with β‐agonist		1015 mg (7×145 mg)	2.5 ml isotonic saline solution	2.5 mg salbutamol	1 mg/kg MP IV
Mahajan	2.5 ml isotonic MgSO4 (6.3%) solution) single dose with β‐agonist		—	2.5 ml saline solution	Albuterol 2.5 mg (0.5 ml)	2 mg/kg prednisolone
Hughes	2.5 ml isotonic MgSO4 (151 mg/dose) (3 doses at 30 min intervals) with β‐agonist		453 mg (3×151 mg)	2.5 ml isotonic saline solution	2.5 mg salbutamol	100 mg hydrocortisone IV
Bessmertny	MgSO4 384 mg (64 mg/ml) in 6 ml sterile water (3 doses at 20 min intervals) after β‐agonist		1152 mg (3×384 mg)	6 ml saline solution	Albuterol 2.5 mg/3 ml	2 mg/kg hydrocortisone IV 6 hourly
Nannini	3 ml isotonic MgSO4 (7.5 g/100 ml) single dose with β‐agonist		225 mg	3 ml saline solution	Salbutamol	None stated
Mangat	3 ml (95 mg) MgSO4 (4 doses, 20 min apart)		380 mg (4×95 mg)	3 ml salbutamol (2.5 mg)	Part of control regimen	100 mg hydrocortisone IV
Meral	2 ml MgSO4 (280 mmol/l)		—	2.5 mg/2.5 ml salbutamol	Part of control regimen	Theophylline

IV, intravenous; MP, methylprednisolone.