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. 2008 Sep 9;337:a1490. doi: 10.1136/bmj.a1490

Table 3.

 Costs (£) associated with treating febrile preschool children with paracetamol, ibuprofen, or both. Values are mean (SD) cost per child by treatment group

Cost item 0-48 hours (intervention period) 0-5 days (total follow-up)
Paracetamol Ibuprofen Paracetamol + ibuprofen Paracetamol Ibuprofen Paracetamol + ibuprofen
NHS costs (n=51) (n=52) (n=51) (n=50) (n=49) (n=51)
Primary care doctor consultations 6.15 (15.41) 3.99 (10.67) 6.48 (13.36) 12.10 (28.30) 10.38 (18.17) 10.23 (14.67)
Primary care nurse consultations 0 0.15 (1.11) 0 0.58 (4.09) 0.16 (1.14) 0
Other primary care consultations 2.03 (7.29) 0 0 3.55 (9.37) 0 0.36 (2.60)
Total primary care cost 8.18 (17.26) 4.14 (11.16) 6.48 (13.36) 16.23 (34.11) 10.54 (18.42) 10.59 (15.16)
A&E 2.78 (13.92) 4.10 (21.84) 1.39 (9.94) 2.84 (14.05) 7.24 (29.86) 2.78 (13.92)
Prescribed drugs 0.37 (1.00) 0.25 (0.85) 0.29 (0.86) 0.56 (1.27) 0.58 (1.43) 0.55 (1.63)
Total NHS cost 11.33 (23.18) 8.49 (29.13) 8.16 (16.36) 19.63 (38.11) 18.36 (40.26) 13.92 (23.17)
Parental costs (n=47) (n=49) (n=47) (n=45) (n=42) (n=43)
Travel cost 0.31 (1.04) 0.02 (0.08) 0.21 (0.74) 0.70 (1.56) 0.29 (0.77) 0.35 (0.89)
Over the counter drugs* 2.52 (0.29) 4.13 (0.00) 6.75 (0.68) 3.69 (1.61) 4.74 (1.44) 7.96 (2.29)
Other expenditure 21.03 (62.18) 16.44 (58.50) 18.10 (51.64) 21.97 (63.41) 24.83 (90.81) 15.64 (46.74)
Total parental costs 23.86 (62.20) 20.60 (58.52) 25.07 (51.60) 26.35 (63.37) 29.90 (90.68) 24.02 (46.36)

A&E=Accident and emergency department.

*Includes cost of study drugs as if parents had bought over the counter.