Table 6.
Sensitivity analyses for different scenarios on costs associated with treating febrile preschool children with paracetamol, ibuprofen, or both
| Different scenarios | Mean (SD) costs | Incremental cost (change from base case) | |||||
|---|---|---|---|---|---|---|---|
| Paracetamol | Ibuprofen | Paracetamol + ibuprofen | Paracetamol + ibuprofen v paracetamol | Paracetamol + ibuprofen v ibuprofen | Ibuprofen v paracetamol | ||
| If study medicines had been prescribed | |||||||
| For 0-48 hours: | |||||||
| NHS costs | 11.69 (22.98) | 11.18 (29.13) | 11.27 (16.36) | −0.42 (2.74) | 0.09 (0.42) | −0.52 (2.32) | |
| Parental costs | 21.88 (62.09) | 16.87 (59.89) | 19.30 (51.39) | −2.58 (−3.78) | 2.43 (−2.04) | −5.01 (−1.74) | |
| For 0-5 days: | |||||||
| NHS costs | 20.00 (37.99) | 20.92 (39.87) | 17.02 (23.18) | −2.98 (2.73) | −3.91 (0.53) | 0.92 (2.20) | |
| Parental costs | 22.88 (63.27) | 25.28 (90.81) | 16.14 (46.68) | −6.73 (−4.13) | −9.14 (−2.48) | 2.40 (−1.65) | |
| If dose by age | |||||||
| Parental costs for 0-5 days | 25.36 (63.27) | 29.41 (90.81) | 22.75 (46.68) | −2.60 (−0.28) | −6.66 (−0.78) | 4.05 (0.50) | |
| Including secondary care costs | |||||||
| NHS costs for 0-5 days | 40.89 (164.8) | 78.64 (268.3) | 35.19 (168.6) | −5.70 (0.01) | −43.45 (−39.01) | 37.75 (39.02) | |
| Parental costs for 0-5 days | 26.89 (63.23) | 31.21 (90.6) | 24.28 (46.3) | −2.60 (−0.27) | −6.92 (−0.26) | 4.32 (0.30) | |