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. 2009 Jan 20;100(3):487–493. doi: 10.1038/sj.bjc.6604885

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Copyright © 2009 Cancer Research UK

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Fluorescence in situ hybridisation targeting ERBB2 in gastric carcinoma specimens (original magnification, × 1000). Red labelled probes target the ERBB2, green labelled probes target chromosome 17 centromere, and nuclei (blue) are stained with DAPI. (A) intestinal type carcinoma (score 0 by IHC) with no ERBB2 amplification; (B) intestinal type carcinoma (score 2+ by IHC) showing ERBB2 amplification; (C) intestinal type carcinoma (score 1+ by IHC) showing ERBB2 amplification. A full colour version of this figure is available at the British Journal of Cancer online.

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