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. 2001 Jan 27;322(7280):210. doi: 10.1136/bmj.322.7280.210

Table.

Cure rate in children prone to otitis either recolonised with α streptococci or given placebo. Values are numbers (percentages) unless stated otherwise

Streptococcal (n=53)* Placebo (n=55) 95% CI P value
Cured 22 (42) 12 (22) 0.028 to 0.372 0.02
Recurrence of otitis media during follow up (92 days) 21 (40) 28 (51) 0.065 to 0.285 0.04
Secretory otitis media at last valid visit 10 15 0.074 to 0.286 0.05
*

12 treated with penicillin and 41 with amoxicillin clavulanic acid. 

10 treated with penicillin and 45 with amoxicillin clavulanic acid. 

Difference between proportion cured with streptococcal spray and proportion cured with placebo.