Table 2.

In vivo ookinete development of KO clones with reduced oocyst numbers.

Exp.	Parasite	Clone	Gct. (%)	n	Mean	SEM	% of wt	P-valuea
I	wt	–	1.4	10	7052	1708	–	–
	Δpsop2	1	1.5	10	456	141	6.5	P < 0.01
II	wt	–	1.2	10	2433	409	–	–
	Δpsop2	1	1.5	10	446	228	18.3	P < 0.01
III	wt	–	2.3	10	1278	404	–	–
	Δpsop2	2	2.4	10	827	744	64.7	P < 0.05
IV	wt	–	2.1	10	1232	669	–	–
	Δpsop2	2	1.1	10	8478	1095	688.1	P < 0.01
I	wt	–	0.9	10	9779	1778	–	–
	Δpsop7	1	1.3	10	6073	1349	62.1	n.s.
II	wt	–	0.4	10	3256	896	–	–
	Δpsop7	1	0.6	10	2332	771	71.6	n.s.
III	wt	–	2.0	10	1671	426	–	–
	Δpsop7	2	2.3	10	6569	1277	393.1	P < 0.01
I	wt	–	2.3	10	1278	404	–	–
	Δpsop9	1	2.0	10	2834	661	221.8	n.s.
II	wt	–	2.1	10	1232	669	–	–
	Δpsop9	1	2.4	10	1538	486	124.8	n.s.
III	wt	–	1.6	10	2543	384	–	–
	Δpsop9	2	1.1	10	2850	694	112.1	n.s.

^aDetermined by Mann–Whitney U-test. Exp., experiment; Gct., gametocytaemia; n.s., not significant.