Table 1.
Compatibility in Qa-1 haplotype between AC-SPL cells and the immunized recipient is necessary for the Suppression of the DTH reaction in the LTS
| IMMUNIZED | H2 | Qa-1 | ACSPL | H2 | Qa-1 | IMM (μm) | IMM+AC-SPL cells (μm) | NAÏVE (μm) |
|---|---|---|---|---|---|---|---|---|
| C3H | k | b | BALB/c | d | b | 360+/−40 | 120+/−18 | 56+/−10 |
| C57BL10.s | s | b | SJL | s | a | 229+/−41 | 300+/−57 | 15+/−5 |
| SJL* | s | a | SJL | s | a | 105+/−20 | 17+/−10 | 3+/−10 |
positive control for C57BL10.s
IMM=immunized
Twenty five thousand AC-SPL cells recovered from TNP-BSA-immunized BALB/c or SJL mice one week after the injection of TNP-BSA into the AC were injected id into a footpad of TNP-BSA- immunized C3H, C57BL10.s or SJL mice immediately after the footpad was challenged with epicutaneous PCl. Swelling was measured 24hr after challenge. Data represents the mean swelling ± SEM of 3 experiments, 9–12 mice/group.