Figure 7.
The hematopoietic differentiation effects caused by AE are dependent on β-catenin function. (a-b) In situ hybridization of gata1 (a) and mpo (b). Knockdown of either β-catenin1 ctnnb1 MO) or β-catenin2 (ctnnb2 MO) restores gata1 expression and suppresses mpo upregulation in the presence of AE. Control, non-injected embryos. Scale bar, 0.3 mm.