. Author manuscript; available in PMC: 2009 Nov 27.

Published in final edited form as: Transplantation. 2008 Nov 27;86(10):1340–1348. doi: 10.1097/TP.0b013e3181891d8b

Table III.

Some Comparisons of Antigen Presentation by Human Endothelial Cells (115) vs. Human Dendritic Cells (116)

Property	Endothelial Cell	Dendritic Cell
Phagocytosis	absent (in vitro only)	present (when immature)
Pinocytosis	active	active
MHC expression	basal; regulated by cytokines	regulated by maturation
Cross presentation	probable	yes
Costimulation	LFA-3 dominant; no B7 (CD80, CD86);	B7 (CD80, CD86) dominant
Adhesion	selective for memory T cells	Cluster with naïve T cells
Activation of T cells	selective for (effector) memory T cells	Preferential with naïve T cells