Table 1.
Estimated Stoichiometries (% ES) of pS78 and pS82 from IP of Hsp27 Before and After Thiolutin Treatmenta
SPAVAAPAYSRALS(78)RQLS(82)SGVSE | |||
---|---|---|---|
Groups | No P | Mono P | Di-P (pS78+pS82) |
IP using anti-Hsp27 Ab | |||
Control | 100% | N.D. | N.D. |
Thiolutin-treated | 32% | 47% at pS82 | 16% |
5% at pS78 | |||
IP using anti-pS78 Hsp27 Ab | |||
Control | N.D. | N.D. | N.D. |
Thiolutin-treated | 17% | 10% at pS82 | 61% |
12% at pS78 |
The %ES was calculated as the measured phosphopeptide divided by the sum of the same peptide with various forms. N.D. means not detected.