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. 2008 Sep 23;337:a1411. doi: 10.1136/bmj.a1411

Table 2.

 Effect of intervention on lung function in children

Variable No of person days No of children Unadjusted Adjusted*
Effect size (β) (95% CI) P value Effect size (β) (95% CI) P value
Amplitude % mean peak expiratory flow rate 26 439 359 1.41 (−2.80 to 5.62) 0.51 1.41 (−2.80 to 5.62) 0.62
Daily FEV1 26 960 360 130.7 (−20.3 to 281.7) 0.09 129.4 (−21.4 to 280.3) 0.09
Morning FEV1 22 157 346 57.6 (−74.8 to 190.1) 0.40 57.0 (−75.4 to 189.4) 0.4
Evening FEV1 23 406 353 121.7 (−37.0 to 280.3) 0.13 120.6 (−38.1 to 279.4) 0.14
Daily peak expiratory flow rate 27 007 360 12.29 (−4.57 to 29.15) 0.15 12.12 (−4.76 to 29.00) 0.16
Morning peak expiratory flow rate 22 450 347 9.01 (−7.54 to 25.56) 0.28 8.92 (−7.66 to 25.50) 0.29
Evening peak expiratory flow rate 23 413 353 12.30 (−4.14 to 28.74) 0.14 12.17 (−4.3 to 28.63) 0.15
Percentage predicted†:
 FEV1 22111 283 2.46 (−11.62 to 16.54) 0.73 2.6 (−11.52 to 16.73) 0.72
 Morning FEV1 18 465 276 −1.07 (−12.62 to 10.49) 0.85 −0.87 (−12.46 to 10.72) 0.88
 Evening FEV1 19 279 280 2.60 (−12.00 to 17.20) 0.73 2.59 (−12.05 to 17.24) 0.73
 Peak expiratory flow rate 22 139 283 3.54 (−1.41 to 8.48) 0.16 3.56 (−1.39 to 8.52) 0.16
 Morning peak expiratory flow rate 18 613 276 2.99 (−1.77 to 7.75) 0.22 3.01 (−1.77 to 7.78) 0.22
 Evening peak expiratory flow rate 19 279 280 3.65 (−1.14 to 8.45) 0.14 3.68 (−1.13 to 8.49) 0.13

FEV1=forced expiratory volume in one second.

ß coefficients are estimated effect size of intervention on peak expiratory flow rate and FEV1.

*Controlled for baseline measure.

†Percentage of predicted FEV1 or peak expiratory flow rate based on 283 available heights.