Table 1.
Baseline characteristics. Values are medians (interquartile ranges) unless stated otherwise
| Characteristics | Aspirin plus antioxidant (n=320) | Aspirin plus placebo (n=318) | Placebo plus antioxidant (n=320) | Placebo plus placebo (n=318) |
|---|---|---|---|---|
| Mean (SD) age (years) | 61.0 (10.0) | 60.0 (10.1) | 60.0 (10.3) | 60.1 (9.7) |
| No (%) women | 169 (53) | 183 (58) | 181 (57) | 180 (57) |
| Time since diagnosis of diabetes (years) | 6.7 (2.9-12.9) | 6.0 (2.7-13.0) | 5.7 (2.4-11.7) | 6.4 (2.6-11.6) |
| No (%) treated with insulin | 107 (33) | 112 (35) | 96 (30) | 91 (29) |
| Smoking status: | ||||
| No (%) current smokers | 105 (33) | 99 (31) | 106 (33) | 87 (27) |
| No (%) former smokers | 113 (35) | 107 (34) | 111 (35) | 116 (36) |
| No (%) never smokers | 102 (32) | 112 (35) | 103 (32) | 115 (36) |
| Body mass index (kg/m2) | 29.7 (26.2-33.3) | 28.7 (25.2-33.0) | 29.4 (26.1-33.5) | 29.2 (25.8-33.2) |
| Mean (SD) systolic blood pressure (mm Hg) | 146 (22) | 143 (21) | 144 (20) | 147 (21) |
| Mean (SD) diastolic blood pressure (mm Hg) | 79 (10) | 78 (10) | 79 (10) | 80 (11) |
| Ankle brachial pressure index | 0.90 (0.82-0.95) | 0.91 (0.84-0.95) | 0.89 (0.81-0.94) | 0.90 (0.83-0.96) |
| Mean (SD) HbA1c level (%) | 8.0 (1.8) | 8.0 (1.7) | 7.9 (1.8) | 7.9 (1.7) |
| Total cholesterol level (mmol/l) | 5.5 (4.8-6.2) | 5.6 (4.9-6.2) | 5.5 (4.9-6.3) | 5.5 (4.9-6.2) |
| Triglyceride level (mmol/l) | 2.2 (1.5-3.2) | 2.2 (1.5-3.3) | 2.3 (1.4-3.4) | 2.1 (1.5-3.3) |
| High density lipoprotein level (mmol/l) | 1.2 (1.0-1.5) | 1.3 (1.0-1.5) | 1.2 (1.0-1.5) | 1.2 (1.0-1.5) |
| Low density lipoprotein level (mmol/l) | 3.1 (2.5-3.7) | 3.1 (2.5-3.7) | 3.2 (2.6-3.9) | 3.1 (2.6-3.7) |