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. 2008 Jun 18;7(8):3102–3113. doi: 10.1021/pr700798h

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Copyright © 2008 U.S. Government

This is an open-access article distributed under the ACS AuthorChoice Terms & Conditions. Any use of this article, must conform to the terms of that license which are available at http://pubs.acs.org.

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ROC curves for the seven triplets giving rise to seven largest AUC, values shown in panel A, when using the profile data. Each search method is abbreviated by its first letter in the figure legend. ROC curves of the first type are displayed in panel A. Panel B shows ROC curves of the second type. Since the total number of spectra in this subset is about 7000, in panel B, the displayed highest number of false positives, 3000, corresponds approximately to E-value of 0.4. We did not show ROC curves of the second type to larger FP value because users probably will not be too interested in the large E-value regime.