Figure 2 Nucleotide sequences of polymorphic regions within the human (A) TNC and (B) COL5A1 genes. (A) The nucleotide sequence, GenBank accession number Z11654, corresponds to part of intron 17 of the TNC gene and contains the GT dinucleotide repeat polymorphism (shown in capital letters). This sequence contains 17 GT dinucleotide repeats. (B) The nucleotide sequence, GenBank accession number AL603650, corresponds to part of the 3′ end (exon 67) of the COL5A1 gene. The positions of two single‐nucleotide polymorphisms (SNPs), together with the restriction enzyme used to genotype individuals for these SNPs, are shown. The alternative nucleotide is given under the wild‐type sequence. The stop codon, as well as the DpnII (GA/TC; rs13946) and BstUI (CG/CG; rs12722) restriction sequences, both located in the 3′‐untranslated region of the gene, are underlined.