Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Induction of weight loss with pharmacotherapy
| Drug | Reference | Patients, n | Duration of therapy, years | Dose, mg | Weight loss outcome, kg (P) |
|---|---|---|---|---|---|
| Sibutramine | Smith IG, Goulder MA (47) | 485 | 1 | 15 od | 6.4 (<0.001) |
| Orlistat | Davidson MH, Hauptman J, DiGirolamo M, et al (57) | 880 | 1 | 120 tid | 8.76 (<0.001) |
| Rimonabant | Pi-Sunyer FX, Aronne LJ, Heshmati HM, et al (58) | 1602 | 1 | 20 od | 6.3 (<0.001) |
od Once daily; tid Three times per day
