FIGURE 3.

Modeling of the active site of AGT-Ma and F152I variant in the PMP form. The putative location of Trp¹⁰⁸ at the active site of AGT-Ma and F152I variant in the PMP form is illustrated. Trp¹⁰⁸, Phe¹⁵², and PMP are represented as blue sticks in AGT-Ma, whereas Trp¹⁰⁸, Ile¹⁵², and PMP are represented as cyano sticks in F152I variant. Oxygen atoms are colored red, nitrogen atoms blue, and phosphorus orange. This figure was rendered using PyMOL (17).