FIGURE 6.
Cytoglobin regulates NO-mediated inhibition of cell respiration. A, representative tracings of O2 detectable in solution upon addition of 2 μm PROLI/NO (t½ 1.8 s) to 5 × 106 cells/ml of the indicated cell type. The arrow indicates addition of donor to both cell lines. The bar indicates 100 s. B, quantitation of the time it took each cell type to return to the rate of oxygen consumption prior to addition of NO. Values represent the mean ± S.E., n = 4. * indicates p < 0.01 as compared with shScrambled, and # indicates p < 0.01 as compared with shCYGB. hCYGB, human CYGB; shScrml, shScrambled.